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A Rab prenyl membrane-anchor allows effector recognition to be regulated by guanine nucleotide.
Lee M, Wickner W, Song H. Lee M, et al. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7739-7744. doi: 10.1073/pnas.2000923117. Epub 2020 Mar 25. Proc Natl Acad Sci U S A. 2020. PMID: 32213587 Free PMC article.
Phosphorylation of HOPS by the vacuolar kinase Yck3 renders fusion strictly dependent on GTP-activated Ypt7, whether bound to membranes by prenyl or transmembrane anchor. The binding of GTP or GDP constitutes a selective switch for Ypt7, but with Ypt7-tm, this switch is on …
Phosphorylation of HOPS by the vacuolar kinase Yck3 renders fusion strictly dependent on GTP-activated Ypt7, whether bound to membranes by p …
Using Community Ecology Theory and Computational Microbiome Methods To Study Human Milk as a Biological System.
Shenhav L, Azad MB. Shenhav L, et al. mSystems. 2022 Feb 22;7(1):e0113221. doi: 10.1128/msystems.01132-21. Epub 2022 Feb 1. mSystems. 2022. PMID: 35103486 Free PMC article. Review.
In this review, we advocate for longitudinal multiomics data collection and demonstrate how incorporating knowledge gleaned from microbial community ecology and computational methods developed for microbiome research can serve as an anchor to advance the study of human mil …
In this review, we advocate for longitudinal multiomics data collection and demonstrate how incorporating knowledge gleaned from microbial c …
Physicochemistry shapes bioactivity landscape of pan-ABC transporter modulators: Anchor point for innovative Alzheimer's disease therapeutics.
Namasivayam V, Stefan K, Gorecki L, Korabecny J, Soukup O, Jansson PJ, Pahnke J, Stefan SM. Namasivayam V, et al. Int J Biol Macromol. 2022 Sep 30;217:775-791. doi: 10.1016/j.ijbiomac.2022.07.062. Epub 2022 Jul 13. Int J Biol Macromol. 2022. PMID: 35839956 Free article.
A cutting-edge strategy to obtain new drug candidates is to explore and potentially exploit the recently proposed multitarget binding site of pan-ABC transporter inhibitors as anchor point for the development of innovative activators to promote Abeta clearance from the bra …
A cutting-edge strategy to obtain new drug candidates is to explore and potentially exploit the recently proposed multitarget binding site o …
Traceability of aquatic animals.
Håstein T, Hill BJ, Berthe F, Lightner DV. Håstein T, et al. Rev Sci Tech. 2001 Aug;20(2):564-83. doi: 10.20506/rst.20.2.1300. Rev Sci Tech. 2001. PMID: 11548527 Free article. Review.
A large variety of physical tagging methods for decapod crustaceans is described, such as the injection of biological stains (fast green, Niagara sky blue, trypan red and blue) and external tags such as coloured streamer tags, wire tags and a variety of anchor tags. Furthe …
A large variety of physical tagging methods for decapod crustaceans is described, such as the injection of biological stains (fast green, Ni …
An altered extracellular matrix-integrin interface contributes to Huntington's disease-associated CNS dysfunction in glial and vascular cells.
Hernandez SJ, Lim RG, Onur T, Dane MA, Smith R, Wang K, Jean GE, Reyes-Ortiz A, Devlin K, Miramontes R, Wu J, Casale M, Kilburn D, Heiser LM, Korkola JE, Van Vactor D, Botas J, Thompson-Peer KL, Thompson LM. Hernandez SJ, et al. Hum Mol Genet. 2023 Apr 20;32(9):1483-1496. doi: 10.1093/hmg/ddac303. Hum Mol Genet. 2023. PMID: 36547263 Free PMC article.
Defining the contribution of these cells to disease can inform cell-type-specific effects and uncover new disease-modifying therapeutic targets. These cells express integrin (ITG) adhesion receptors that anchor the cells to the extracellular matrix (ECM) to maintain the in …
Defining the contribution of these cells to disease can inform cell-type-specific effects and uncover new disease-modifying therapeutic targ …
The CCG-domain-containing subunit SdhE of succinate:quinone oxidoreductase from Sulfolobus solfataricus P2 binds a [4Fe-4S] cluster.
Hamann N, Bill E, Shokes JE, Scott RA, Bennati M, Hedderich R. Hamann N, et al. J Biol Inorg Chem. 2009 Mar;14(3):457-70. doi: 10.1007/s00775-008-0462-8. Epub 2008 Dec 16. J Biol Inorg Chem. 2009. PMID: 19085017 Free PMC article.
In type E succinate:quinone reductase (SQR), subunit SdhE (formerly SdhC) is thought to function as monotopic membrane anchor of the enzyme. SdhE contains two copies of a cysteine-rich sequence motif (CX(n)CCGX(m)CXXC), designated as the CCG domain in the Pfam database and …
In type E succinate:quinone reductase (SQR), subunit SdhE (formerly SdhC) is thought to function as monotopic membrane anchor of the …
Common values in assessing health outcomes from disease and injury: disability weights measurement study for the Global Burden of Disease Study 2010.
Salomon JA, Vos T, Hogan DR, Gagnon M, Naghavi M, Mokdad A, Begum N, Shah R, Karyana M, Kosen S, Farje MR, Moncada G, Dutta A, Sazawal S, Dyer A, Seiler J, Aboyans V, Baker L, Baxter A, Benjamin EJ, Bhalla K, Bin Abdulhak A, Blyth F, Bourne R, Braithwaite T, Brooks P, Brugha TS, Bryan-Hancock C, Buchbinder R, Burney P, Calabria B, Chen H, Chugh SS, Cooley R, Criqui MH, Cross M, Dabhadkar KC, Dahodwala N, Davis A, Degenhardt L, Díaz-Torné C, Dorsey ER, Driscoll T, Edmond K, Elbaz A, Ezzati M, Feigin V, Ferri CP, Flaxman AD, Flood L, Fransen M, Fuse K, Gabbe BJ, Gillum RF, Haagsma J, Harrison JE, Havmoeller R, Hay RJ, Hel-Baqui A, Hoek HW, Hoffman H, Hogeland E, Hoy D, Jarvis D, Karthikeyan G, Knowlton LM, Lathlean T, Leasher JL, Lim SS, Lipshultz SE, Lopez AD, Lozano R, Lyons R, Malekzadeh R, Marcenes W, March L, Margolis DJ, McGill N, McGrath J, Mensah GA, Meyer AC, Michaud C, Moran A, Mori R, Murdoch ME, Naldi L, Newton CR, Norman R, Omer SB, Osborne R, Pearce N, Perez-Ruiz F, Perico N, Pesudovs K, Phillips D, Pourmalek F, Prince M, Rehm JT, Remuzzi G, Richardson K, Room R, Saha S, Sampson U, Sanchez-Riera L, Segui-Gomez M, Shahraz S, Shibuya K, Singh D, Sliwa K, Smith E, Soerjom… See abstract for full author list ➔ Salomon JA, et al. Lancet. 2012 Dec 15;380(9859):2129-43. doi: 10.1016/S0140-6736(12)61680-8. Lancet. 2012. PMID: 23245605 Free PMC article.
We used results from the population health equivalence responses to anchor the results from the paired comparisons on the disability weight scale from 0 (implying no loss of health) to 1 (implying a health loss equivalent to death). ...By contrast with the popular hypothes …
We used results from the population health equivalence responses to anchor the results from the paired comparisons on the disability …
Cytoskeleton and tissue origin in the anterior cynomolgus monkey eye.
Hamanaka T, Thornell LE, Bill A. Hamanaka T, et al. Jpn J Ophthalmol. 1997 May-Jun;41(3):138-49. doi: 10.1016/s0021-5155(97)00031-2. Jpn J Ophthalmol. 1997. PMID: 9243309
Cells in the deep sclera adjacent to the supraciliary space stained with antibodies to smooth muscle alpha-actin, alpha-vinculin, talin, and desmin. These cells may anchor ciliary muscle cells into the sclera or may be developmental remnants of ciliary muscle cells. ...
Cells in the deep sclera adjacent to the supraciliary space stained with antibodies to smooth muscle alpha-actin, alpha-vinculin, talin, and …
Effects of applied contact force and volume control setting on output force levels of the BAHA Softband.
Hodgetts WE, Scollie SD, Swain R. Hodgetts WE, et al. Int J Audiol. 2006 May;45(5):301-8. doi: 10.1080/14992020600582133. Int J Audiol. 2006. PMID: 16717021
The BAHA Softband has been developed to provide a transcutaneous anchor for a BAHA until a child is a surgical candidate for the percutaneous BAHA implant. ...
The BAHA Softband has been developed to provide a transcutaneous anchor for a BAHA until a child is a surgical candidate for the perc …